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Pefcalcitol

Pefcalcitol 381212-03-9
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Chemical Information
Product name:Pefcalcitol Purity:NLT 98%
CAS NO:381212-03-9 Solubility:
Molecular Formula:C₂₆H₃₄F₅NO₄ Package:Customizable upon request
Molecular Weight:519.54 g/mol Storage:
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Remarks
A novel antipsoriatic prodrug candidate containing a 16-en-22-oxa-vitamin D₃ structure; a vitamin D₃ analog (VDR agonist) designed for topical treatment of psoriasis; also reported to possess phosphodiesterase (PDE) inhibitory activity
References

[1] Psomadakis, C. E.; Han, G. Novel Topical Therapies for Psoriasis and Atopic Dermatitis. J. Clin. Aesthet. Dermatol. 2019, *12* (12), 28–34. Published online December 1, 2019. PMID: 32038762; PMCID: PMC7002051.

[2] Takeiri, A.; Tanaka, K.; Harada, A.; Matsuzaki, K.; Yano, M.; Motoyama, S.; Katoh, C.; Mishima, M. Giemsa-stained pseudo-micronuclei in rat skin treated with vitamin D₃ analog, pefcalcitol. Genes Environ. 2017, *39*, 17. DOI: 10.1186/s41021-017-0077-9. PMID: 28580039; PMCID: PMC5452393.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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