TEI-9647

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Chemical Information

Product name：TEI-9647	Purity：NLT98%
CAS NO：173388-20-0	Solubility：
Molecular Formula：C₂₇H₃₈O₄	Package：Customizable upon request
Molecular Weight：426.59	Storage：Dry, dark; short-term (days to weeks) at 0–4°C; long-term (months to years) at –20°C.

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Remarks

TEI-9647 is a vitamin D antagonist that inhibits 1α,25-dihydroxyvitamin D₃-induced osteoclast formation by bone marrow cells from patients with Paget's disease.

References

1，Yamaoka K, Kim MS, Takada I, Takeyama K, Kamimura T, Kato S. Serum in culture changes vitamin D analog TEI-9647 from agonist to antagonist. J Steroid Biochem Mol Biol. 2006 Aug;100(4-5):177-83. Epub 2006 Jul 10. PubMed PMID: 16835013.
2，Ishizuka S, Kurihara N, Miura D, Takenouchi K, Cornish J, Cundy T, Reddy SV, Roodman GD. Vitamin D antagonist TEI-9647 inhibits osteoclast formation induced by 1α,25-dihydroxyvitamin D₃ from Paget's bone marrow cells. J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):331-4. PubMed PMID: 15225795.
3，Takenouchi K, Sogawa R, Manabe K, Saitoh H, Gao Q, Miura D, Ishizuka S. Synthesis and structure-activity relationships of TEI-9647 derivatives as vitamin D₃ antagonists. J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):31-4. PubMed PMID: 15225742.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

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