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   CAS NO.    Products Name
   453562-69-1 Motesanib  more...
   Motesanib (AMG-706) is an orally bioavailable diphosphate salt of a multiple receptor tyrosine kinase inhibitor with potential antineoplastic activity[1]. This reagent selectively targe...
   635702-64-6 Pazopanib hydrochloride  more...
   VEGFR enzyme assays for VEGGR1,VEGFR2, and VEGFR3 were running in homogeneous time-resolved fluorescence (HTRF) format in 384-well microtiter plates using a purified, baculovirus-expres...
   219580-11-7 PD173074  more...
   PD173074 is a potent ATP-competitive, reversible FGFR and VEGFR inhibitor with IC50 of 5, 21.5 and ~100 nM for FGFR3, FGFR1 and VEGFR2, respectively.PD173074 is a cell-permeable pyridop...
   1042385-75-0 PF-00299804 dacomitinib  more...
   PF299804 is a potent, orally available, irreversible tyrosine kinase HER 1 (EGFR), HER2 and HER4 inhibitor with IC50 of 6, 45.7 and 73.7 nM for EGFR, ERBB2 and ERBB4, respectively.PF299...
   444731-52-6 Pazopanib  more...
   VEGFR enzyme assays for VEGGR1,VEGFR2, and VEGFR3 were running in homogeneous time-resolved fluorescence (HTRF) format in 384-well microtiter plates using a purified, baculovirus-expres...
    SAR131675  more...
   SAR131675 dose dependently inhibits the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD, with an IC50 of about 20 nM. SAR131675 dose depen...
   204005-46-9 Semaxanib(SU5416)  more...
   Semaxanib, also known as SU5416, is a quinolone derivative with potential antineoplastic activity. Semaxanib reversibly inhibits ATP binding to the tyrosine kinase domain of vascular en...
   332012-40-5 Telatinib (BAY 57-9352)  more...
   Telatinib has 0.66, 0.17, and 2.5 times higher IC50 values for VEGFR3, c-Kit, and PDGFRβ than VEGFR2, respectively, while Vatalanib exhibits 18, 20, and 16 times higher IC50 values, res...
   252916-29-3 TSU-68  more...
   TSU-68 has significant antitumor activity against many types of tumor xenograft explants in athymic mice. TSU-68 inhibits angiogenesis through several mechanisms, including the inductio...
   475108-18-0 Tivozanib(AV-951)  more...
   AV-951(Tivozanib) is an orally bioavailable potent VEGFR-1, 2 and 3, cKit and PDGFR inhibitor with IC50 of 0.21, 0.16, 0.24, 1.63 and 1.72 nM, respectively.AV-951(Tivozanib) has potenti...

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