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   CAS NO.    Products Name
   928326-83-4 BIBF-1120  more...
   BIBF1120 inhibits PDGFR kinase activity of PDGFR alpha and PDGFR beta types with IC50 values of 59 and 65 nM, respectively. In addition, BIBF1120 suppresses the FGFR subtypes with IC50 ...
   1174046-72-0 BMS 794833  more...
   BMS-794833,a potent ATPcompetitive Met/VEGFR-2 kinase inhibitor,demonstrates enhanced activity versus both Met-dependent and Met-insensitive tumor lines. BMS-794833 also inhibits Ron (M...
   649735-46-6 Brivanib(BMS-540215)  more...
   Brivanib (BMS-540215) is hydrolyzed to the active moiety BMS-540215 in vivo. BMS-540215 shows potent and selective inhibition of VEGFR and FGFR tyrosine kinases . BMS-540215 is an ATP-c...
   649735-63-7 Brivanib alaninate (BMS-582664)  more...
   BMS-582664 inhibits VEGF-stimulated and FGF-stimulated proliferating of HUVECs with IC50 of 40 nM and 276 nM. BMS-582664 (2 μM) significantly inhibits VEGFR2, FGFR1, ERK1/2 and Akt phos...
   849217-68-1 Cabozantinib  more...
   XL-184 free base (Cabozantinib) is a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and K...
   1140909-48-3 Cabozantinib (S)-malate  more...
   XL-184 free base (Cabozantinib) is a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and K...
   288383-20-0 Cediranib (AZD2171)  more...
   Cediranib suppresses PDGF-AA with an IC50 of 0.04 μM in MG63 cell lines. Cediranib has been shown to block Flt-1-associated kinase with an IC50 of 5 nM and VEGF-C and VEGF-D receptor Fl...
   417716-92-8 E7080 lenvatinib  more...
   E7080 is the most potent dual inhibitor of VEGF-R3 tyrosine kinase (IC50=5.2 nM) as well as VEGF-R2 tyrosine kinase (IC50=4.0 nM) among those small-molecule inhibitors of VEGF-R kinases...
   796967-16-3 Linifanib abt869  more...
   Linifanib (ABT-869) is a structurally novel, potent RTK and VEGF and PDGF receptor families inhibitor with IC50 of 0.2, 2, 4, and 7 nM for human endothelial cells, PDGFR-β, KDR, and CSF...
   857876-30-3 Motesanib diphosphate  more...
   Motesanib (AMG-706) is an orally bioavailable diphosphate salt of a multiple receptor tyrosine kinase inhibitor with potential antineoplastic activity[1]. This reagent selectively targe...

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