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   CAS NO.    Products Name
   552325-73-2 A 674563  more...
   A-674563 is achieved from A-443654 by replacing the indole with a phenyl moiety and getting oral activity. A-674563 slows proliferation of tumor cells with EC50 of 0.4 μM. A-674563 does...
   885499-61-6 CCT128930  more...
   CCT128930 is a novel potent ATP-competitive, AKT inhibitor with an IC50 of 6 nM. CCT128930 prevents AKT activity in vitro and in vivo and induces marked antitumor responses. CCT128930 s...
   937174-76-0 GSK 690693  more...
   GSK690693 is an aminofurazan-derived,novel ATP-competitive, low-nanomolar pan-Akt kinase inhibitor. It is selective for the Akt isoforms(inhibits Akt kinases 1, 2, and 3 with IC50 value...
   1032350-13-2 MK-2206  more...
   MK-2206, a highly selective non-ATP competitive allosteric Akti, has nM IC50 and broad preclinical antitumor activity. MK-2206 is a potent allosteric Akt inhibitor with IC50 at 8 nm, 2 ...
   1191951-57-1 PHT-427  more...
   PHT-427 is a dual Akt and PDPK1 inhibitor that affects downstream targetsamong sensitive but not resistant cells and tumor xenografts. When given orally, PHT-427 inhibited the growth of...
   1013101-36-4 PF 04691502  more...
   PF-04691502 is a potent and selective dual PI3K/mTOR inhibitor to phosphorylation of AKT T308 and AKT S473 with IC50 of 7.5 and 3.8 nM, respectively. PF-04691502 is an ATP-competitive i...
   35943-35-2 Triciribine  more...
   Triciribine is a synthetic tricyclic nucleoside which acts as a specific inhibitor of the Akt signaling pathway. It selectively inhibits the phosphorylation and activation of Akt1, -2 a...

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