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   CAS NO.    Products Name
   781661-94-7 YM 155  more...
   YM155 is not sensitive to survivn gene promoter-driven luciferase reporter activity even at 30 μM. YM155 significantly inhibits endogenous survivin expression in PC-3 and PPC-1 human HR...
   1037184-44-3 YK 4-279  more...
   
   288250-47-5 Y320;Y-320  more...
   Y-320 is a new phenylpyrazoleanilide immunomodulator; inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM....
   132836-42-1 YS-49  more...
   
   146986-50-7 Y27632  more...
   Activation of excitatory receptors coupled to G-proteins can cause contraction of smooth muscle by increasing Ca2+-sensitivity without changing [Ca2+]. This pathway involves RhoA, a sma...
   129830-38-2 Y 27632 dihydrochloride  more...
   Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK....
   209984-56-5 YO-01027  more...
   YO-01027 interacts directly with theγ-secretase complex and targets the N-terminal Presenilin fragment. Increasing concentrations of YO-01027 administered to APPL- or Notch-expressing c...
   187389-52-2 Z-VAD-FMK  more...
   Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor, blocks all features of apoptosis in THP.1 and Jurkat T-cells.Z-VAD-FMK (10 mM) inhibits apoptosis in THP.1 cells. Z-VA...
   475110-96-4 ZSTK 474  more...
   ZSTK474 inhibits class I PI3K isoforms with IC50 of 37 nM, mostly PI3Kδ....
   49671-76-3 ZLN005  more...
   ZLN005 is a novel transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α)....

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