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   CAS NO.    Products Name
   1446502-11-9 Enasidenib  more...
   Enasidenib is a oral potent, selective, reversible inhibitor of mutant IDH2. ...
   223104-29-8 SEA 0400  more...
   SEA0400 is a novel and selective inhibitor of the Na+-Ca2+ exchanger with IC50 of 5-33 nM (inhibiting Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia)....
   1038915-60-4 Niraparib  more...
   MK-4827(Niraparib) is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PAR...
   896720-20-0 VX-11e  more...
   VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK (Extracellular Signal-Regulated Kinase); antitumor agent. IC50 value: Target: ERK...
   1204669-58-8 INCB024360  more...
   INCB 024360 is a potent and novel indoleamine-2,3 dioxygenase (IDO)inhibitor with an IC50 value <100 nM. IC50 Value: <100 nM [1] Target: Indoleamine-2,3-dioxygenase IDO is an immunomodu...
   224452-66-8 Retapamulin SB-275833  more...
   Retapamulin SB-275833 is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with Kd of 3 nM....
   1197953-54-0 Brigatinib (AP-26113)  more...
   Brigatinib is a highly potent and selective investigational ALK inhibitor with mean IC50 value < 100 nM in Ba/F3 cells. IC50 value: < 100 nM Target: pan-ALK in vitro: Brigatinib inhibit...
   1357470-29-1 ON123300  more...
   8-Cyclopentyl-7,8-dihydro-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-7-oxo-pyrido[2,3-d]pyrimidine-6-carbonitrile...
   102121-60-8 AM 580  more...
   AM580(Am-580; Ro 40-6055; NSC608001; CD336) is a stable retinobenzoic derivative originally synthesized as a RARα agonist. IC50 value: Target: RARα agonist in vitro: AM580 is a powerful...
   847559-80-2 NVP-BEP800  more...
   NVP-BEP800 is a novel, fully synthetic HSP90β inhibitor with IC50 of 58 nM, exhibits>70-fold selectivity against Hsp90 family members Grp94 and Trap-1...

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