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   CAS NO.    Products Name
   1025720-94-8 BMS777607  more...
   BMS 777607 is a Small-Molecule Met Kinase Inhibitor with an IC50 of < 0.1 μM. Its treatment had little effect on tumor cell growth but inhibited cell scattering activated by exogenous...
   146426-40-6 Flavopiridol (Alvocidib)  more...
   Flavopiridol is a Phase 3 clinical trials in high anticancer drugs, can be used for the treatment of chronic lymphocytic leukemia....
   606143-52-6 Selumetinib  more...
   AZD6244 is not competitive with ATP and inactivates the ERK1/2 phosphorylation with IC50 concentrations below 40 nM. AZD6244 also inhibits the growth of primary HCC cells through inhibi...
   162808-62-0 Caspofungin  more...
   Caspofungin is a fermented product Glarea Lozoyensis synthetic semi-synthetic lipopeptide (echinocandin) compound. Caspofungin made ​​a number of filamentous fungi and yeast...
   1193782-16-9 N-((2-hydroxy-1-hydroxymethyl)ethyl)-9-oxo-11.alpha.,15S-dihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-amide  more...
   17-phenyl trinor PGE2 serinol amide (17-phenyl trinor PGE2-SA) is a stable analog of PGE2 2-glyceryl ester that has been modified to increase receptor binding affinity. The biological a...
   38315-43-4 17-phenyl trinor PGE2  more...
   17-phenyl trinor PGE2 is a synthetic analog of PGE2. It is an EP1 and EP3 receptor agonist.1↗,2↗ 17-phenyl trinor PGE2 causes contraction of the guinea pig ileum at a concentration of 1...
   918505-84-7 PLX 4720  more...
   Biological Activity of PLX-4720: PLX4720, a 7-azaindole derivative that inhibits B-RafV600E with an IC50 of 13 nM, defines a class of kinase inhibitor with marked selectivity in ...
   212631-79-3 PD 184352  more...
   PD 184352/CI-1040 is a non-competitive inhibitor of MEK1/2 with a Ki of 300nM in vitro CI-1040 inhibited MEK (as measured by phosphorylated ERK (p-ERK) levels) with a half-maximal inhib...
   285983-48-4 Doramapimod BIRB 796  more...
   Doramapimod is a small molecule p38 MAPK inhibitor with an Kd of 0.1 nM. It is more potent than SB 203580 on p38α and p38β MAPKs; It is a potential agent for the treatment of inflamma...
   477600-75-2 CP 690550  more...
   The somatic activating janus kinase 2 mutation (JAK2)V617F is detectable in most patients with polycythemia vera (PV). Enzymatic assays indicate that both JAK1 and JAK2 are 100- and 20-...

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