Home Products PLX 4720
PLX 4720
Synonyms:
CAS NO: 918505-84-7
Molecular Formula: C17H14ClF2N3O3S
Molecular Weight: 413.83
Purity: 99%
Solubility: In DMSO
Storage: −20°C
Availability and Price
If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.
Order       Order Infomation
Shipping and handling fee USD40
Free delivery is qualified when the total value of your order exceeds 500USD
Remarks: Biological Activity of PLX-4720: PLX4720, a 7-azaindole derivative that inhibits B-RafV600E with an IC50 of 13 nM, defines a class of kinase inhibitor with marked selectivity in both biochemical and cellular assays. PLX4720 preferentially inhibits the active B-RafV600E kinase compared with a broad spectrum of other kinases (IC50:B-Raf=160 nM, BRK=130 nM, other kinases >1000nM), and potent cytotoxic effects are also exclusive to cells bearing the V600E allele (GI50<1.7 M, while other wild cell GI50>10M).

Quality Control

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
Related Products
Raf Inhibitors
 

None of the products will be supplied to countries in which this could be in conflict with the existing patents. However the final responsibility lies with the Buyer.

Our products are for research use only, not for human use.
 
Homepage | About Us | Products | News&Events | Custom Synthesis | Order Infomation | Contact Us
Friendly link: molbase   Copyright © Taizhou Crene Biotechnology Co.,Ltd. 技术支持:趋势科技