Home Products ML385
ML385
Synonyms:
CAS NO: 846557-71-9
Molecular Formula: C29H25N3O4S
Molecular Weight: 511.59
Purity: 98% min
Solubility: DMSO
Storage: -20°C
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Remarks: ML385 interacts with NRF2 and affects the DNA binding activity of the NRF2-MAFG protein complex. The addition of ML385 decreases anisotropy in a dose-dependent manner, with an IC50 of 1.9 ¦ÌM. A dose-dependent reduction in the NRF2 transcriptional activity is observed and the maximum inhibitory concentration is 5 ¦ÌM by ML385. Treatment with ML385 leads to a significant reduction in NRF2 and downstream target gene expression selectively in KEAP1 mutant H460 cells. ML385 selectively affects the colony forming ability or growth of lung cancer cells with gain of NRF2 function.

Quality Control

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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XL388
XL-765, SAR245409
XEN445
XMD17-109
XMD 8-92
Y27632
Y320;Y-320
YM 155
YS-49
YK 4-279
YM90Khydrochloride
Y 27632 dihydrochloride
Z-JIB-04 (NSC 693627)
ZLN005
ZSTK 474
Z-VAD-FMK
ZM 241385
ZM323881
Zotarolimus A179578 ABT 578
Zibotentan
Zonisamide sodium salt
[1,1’-Biphenyl]-4-carboxylic acid, (3aR,4R,5R,6aS)-4-[(1E,3S)-3-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-5- phenyl-1-pentenyl]hexahydro-2-oxo-2H-cyclopenta[b]furan-5-yl ester
[2,8-Bis(trifluoromethyl)-4-quinolinyl]-2-pyridinylmethanone
 

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Our products are for research use only, not for human use.
 
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