Home Products OSI-930
OSI-930
Synonyms:
CAS NO: 728033-96-3
Molecular Formula: C22H16F3N3O2S
Molecular Weight: 443.44
Purity: 98% min
Solubility: In DMSO
Storage: -20°C
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Remarks: OSI-930 is a multi-targeted tyrosine kinase inhibitor that is designed to act as a potent co-inhibitor of the receptor tyrosine kinases c-Kit (IC50:9.5nM) and VEGFR-2 (IC50:10.1nM).OSI-930 targets both cancer cell proliferation and blood vessel growth (angiogenesis) in selected tumors. In preclinical studies, OSI-930 shows broad efficacy in tumor models representative of small cell lung cancer, glioblastoma, colorectal, renal, head and neck, non-small cell lung cancer and gastric cancers.

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