Home Products AS-605240
CAS NO: 648450-29-7
Molecular Formula: C12H7N3O2S
Molecular Weight: 257.27
Purity: 98% min
Solubility: In DMSO
Storage: −20°C
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Remarks: AS-605240 is a PI3K inhibitor (IC50 at 8 nM), which displays 30-fold selectivity over PI3K and PI3K and 7.5-fold selectivity over PI3K. This agent is the first examples of selective PI3K inhibitors, and was used to block neutrophil chemotaxis in vitro and in vivo. In passive mouse models for rheumatoid arthritis these compounds minimized progression of joint destruction.

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