Home Products Belinostat (PXD101)
Belinostat (PXD101)
Synonyms: PX105684
CAS NO: 414864-00-9
Molecular Formula: C15H14N2O4S
Molecular Weight: 318.35
Purity: 98% min
Solubility: In DMSO
Storage: −20°C
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Remarks: Belinostat (PXD101) is a novel hydroxamate-type inhibitor of histone deacetylase (HDAC) activity. Belinostat inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM. PXD101 is cytotoxic in vitro in a number of tumor cell lines with IC50s in the range of 0.2-3.4 uM as determined by a clonogenic assay and induces apoptosis.

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