Home Products Mivebresib£»ABBV-075
Mivebresib£»ABBV-075
Synonyms:
CAS NO: 1445993-26-9
Molecular Formula: C22H19F2N3O4S
Molecular Weight: 459.47
Purity: 98% min
Solubility: DMSO
Storage: -20¡æ
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Remarks: Mivebresib, also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-containing proteind) with potential antineoplastic activity. Upon administration, the bromodomain inhibitor ABBV-075 binds to the acetyl-lysine binding site in the BRD of certain BRD-containing protein(s), thereby preventing the interaction between those proteins and acetylated histones. This disrupts chromatin remodeling, prevents the expression of certain growth-promoting genes, and leads to an inhibition of cell growth in susceptible tumors.

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Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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ZLN005
[2,8-Bis(trifluoromethyl)-4-quinolinyl]-2-pyridinylmethanone
 

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Our products are for research use only, not for human use.
 
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