Home Products MK-2206
CAS NO: 1032350-13-2
Molecular Formula: C25H21N5O.2HCl
Molecular Weight: 480.39
Purity: 98% min
Solubility: In DMSO
Storage: −20°C
Availability and Price
If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.
Order       Order Infomation
Shipping and handling fee USD40
Free delivery is qualified when the total value of your order exceeds 500USD
Remarks: MK-2206, a highly selective non-ATP competitive allosteric Akti, has nM IC50 and broad preclinical antitumor activity. MK-2206 is a potent allosteric Akt inhibitor with IC50 at 8 nm, 2 mM, 65 mM for Akt1, Akt2 and Akt3 respectively. 1 hr treatment of 1 M MK-2206 abolished Akt phosphorylation in U87MG cells. MK-2206 treatment abolished IR-induced Akt phosphorylation. Moreover, treatment with MK-2206 also increased the radiosensitivity of U87MG cells.

Quality Control

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
Related Products
AKT Inhibitors

None of the products will be supplied to countries in which this could be in conflict with the existing patents. However the final responsibility lies with the Buyer.

Our products are for research use only, not for human use.
Homepage | About Us | Products | News&Events | Custom Synthesis | Order Infomation | Contact Us
Friendly link: molbase   Copyright © Taizhou Crene Biotechnology Co.,Ltd. 技术支持:趋势科技